Jin-Tai Yu has been dedicated to precise prevention, diagnosis, and treatment research of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Based on the multi-omics data of established large cohorts, Jin-Tai Yu utilizes artificial intelligence to search for novel targets for neurodegenerative diseases and further dissects potential pathogenic mechanisms of identified targets through basic research. He aims to develop novel strategies for prevention, diagnosis, and treatment of neurodegenerative diseases.